I have my mother fighting against breast cancer. We almost went till a moment where we thought we are in a losing game, but touch wood, we are fighting back again. Some one referred an complementing medicine to Alopathic Cancer Treatment, which is more on the Chemo or Radiation. This medication is based on the leaves and bark extract of a commonly growing tree and this treatment has no side effects and pretty simple to follow.
The tree is called as Simarouba Glauca and it is native to South America, Known to grow in the harder terrains and requires no care at all once it actually finds roots after planting. There are a lot of articles on this tree in the net, but they are more on the commercial yields like the oil and fruit pulp etc., but little less on the medicinal properties of the tree. Was googling a lot on this tree and its uses and in specific for some scientific papers on the same and found some. Just wanted to write this post so that it might help others who might find this useful and fighting cancer. Wanted to give a live case scenario based on our use and also the scientific paper which I dig one.
My Mother is undergoing the Secondary Chemotherapy Treatment and this time she is on Paclitaxel. On Weekly Dosage. For the first weeks, the WBC, Haemoglobin and RBC count where contantly dropping and the common side effect of Nausea and disturbance in Bowel movements and loss of Appetite.
We went and met these people who suggested this treatment and started the Simarouba Leaves treatment along with the weekly chemotherapy. In our Preliminary Chemotherapy which was done in end of 2009, From the third cycle she started getting deteriorating on the above said side effects and got worsened till she completed the sixth Cycle. Not to mention the Loss of Hair and Darkening of Nails.
This time, there was a change. Once we started this therapy, the blood count became normal. There is Loss of hair and darkening of nails, but comparatively, the loss of appetite and disturbance in bowel movements is more or less nil. She cooks her own food and she is on her own. Her Haemoglobin has been always around 8.5 yo 9.5 and WBC above normal levels.
The Tolerance level is much higher and in the CT done in the end of Sixth Cycle in the secondary Chemo, there was a considerable reduction in the Tumor size. In short, We definitely feel its working.
//Another area of research on simarouba and its plant chemicals has focused on cancer and leukemia. The quassinoids responsible for the anti-amebic and antimalarial properties have also shown in clinical research to possess active cancer-killing properties. Early cancer screening performed by the National Cancer Institute in 1976 indicated that an alcohol extract of simarouba root (and a water extract of its seeds) had toxic actions against cancer cells at very low dosages (less than 20 mcg/ml). Following up on that initial screening, scientists discovered that several of the quassinoids in simarouba (glaucarubinone, alianthinone, and dehydroglaucarubinone) had antileukemic actions against lymphocytic leukemia in vitro and published several studies in 1977 and 1978. Researchers found that yet another simarouba quassinoid, holacanthone, also possessed antileukemic and antitumorous actions in 1983. Researchers in the UK cited the antitumorous activity of two of the quassinoids, ailanthinone and glaucarubinone, against human epidermoid carcinoma of the pharynx. A later study in 1998 by U.S. researchers demonstrated the antitumorous activity of glaucarubinone against solid tumors (human and mouse cell lines), multi-drug-resistant mammary tumors in mice, and antileukemic activity against leukemia in mice.//
I googled for some detail on the Quassinoid which is told to be glaucarubinone, the major component in the Simarouba Glauca leaves.
This talks on the AntiCancer properties of Glaucarubinone
A series of glaucarubinone analogues, obtained from natural sources as well as synthesized by us, were studied both in vitro and in vivo. The focus of the in vitro assessment was to define solid tumor-selective compounds by quantitating differential cytotoxic activity between murine and human solid tumor cells and either murine leukemia or normal cells. Subsequent in vivo studies were aimed at determining the therapeutic efficacy of these analogues against the murine models. Structure-activity analysis consequent to both the in vitro and in vivo studies demonstrated that few changes could be made in the parent glaucarubinone structure (outside of the C-15 position) without abrogating either cytotoxicity or potency. However, significant changes could be made at the C-15 position which modified, either enhanced or diminished, in vitro differential cytotoxicity, potency, human solid tumor selectively, and differential cytotoxicity to a MDR-expressing murine mammary tumor.
This is a published Medical Article in the National Center for Biotechnology Information.
To Conclude, When you actually see your near and dears struggling with a chronic disease, you tend to do anything and everything possible to keep the pain down. This is was one such try which has made me feel that it has done some help to her. Sharing my experience so that it might be useful to someone some where.
Photograph Courtesy : Ed Weislo, floridasnature.com